Around 450 jobs will be cut from BBC News under plans to complete its £80m savings target by 2022.
There will be a reduction in the number of films produced by Newsnight, which will lead to post closures on the BBC Two programme.
There will also be job closures at BBC Radio 5 Live and the World Update programme on the World Service.
BBC News boss Fran Unsworth said there had to be a move away from traditional broadcasting and towards digital.
The job cuts announced on Wednesday include the previously announced closure of BBC Two’s Victoria Derbyshire programme.
BBC News currently employs around 6,000 people, including 1,700 outside the UK. Its budget after the changes will be around £480m per year.
Unsworth, who is director of BBC News, said: “The BBC has to face up to the changing way audiences are using us.
“We need to reshape BBC News for the next five to 10 years in a way which saves substantial amounts of money. We are spending too much of our resources on traditional linear broadcasting and not enough on digital.”
What will be cut?
The corporation announced in 2016 that it needed to save £800m, with around £80m of that figure coming from News.
Just over £40m – around half – of the savings required in BBC News have already been found over the past four years.
The remaining savings will be found in large part by restructuring the newsroom to adopt a “story-led” model, which will see planned stories each rolled out across a greater number of programmes and outlets.
The BBC said this would avoid the duplication that occurs from several programmes putting resources into the same news stories.
However, the changes mean there will be a reduction in the overall number of stories covered.
Unsworth said there would be a review of the number of presenters BBC News has and how they work, but there are unlikely to be any further closures of entire programmes or services.
The savings are expected to result in post closures across BBC News as the planning and commissioning of stories is centralised.
The BBC News website will be largely, although not entirely, protected, as the corporation prepares to invest further in digital, including the launch of a new BBC News app.
The 450 job cuts include around 50 post closures at the World Service that were announced at the end of 2019.